Every minute counts: A comparison of thawing times and haemostatic quality of plasma thawed at 37degreeC and 45degreeC using four different methods

Abstract

Background: Having faster plasma thawing devices could be beneficial for transfusion services, as it may improve the rapid availability of thawed plasma for bleeding patients, and it might remove the need to have extended pre-thawed plasma: thus, reducing unnecessary plasma wastage. Study Design and Methods: The aims of this study were to assess (a) the thawing times and (b) in vitro haemostatic quality of thawed plasma using Barkey Plasmatherm V (PTV) at 37 and 45degreeC versus Barkey Plasmatherm Classic (PTC) at 37 and 45degreeC, Sarstedt Sahara-III Maxitherm (SS-III) at 37degreeC and Helmer Scientific Thermogenesis Thermoline (TT) at 37degreeC. Haemostatic quality was assessed using LG-Octaplas at three different time points: baseline (5 min), 24 and 120 h after thawing.