Clinical presentation of monkeypox in people with and without HIV in the United Kingdom during the 2022 global outbreak

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Authors

Pilkington, Victoria
Quinn, Killian
Campbell, Lucy
Payne, Lara
Brady, Michael
Post, Frank A.

Issue Date

2023

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Article

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Abstract

Early UK surveillance data revealed that people living with HIV were overrepresented among cases of monkeypox (mpox). However, it remains unknown whether mpox infection is more severe in people living with well-controlled HIV. All laboratory-confirmed mpox cases presenting between May and December 2022 to one London hospital service were identified via pathology reporting systems. We extracted demographic and clinical data to allow comparison of clinical presentation and severity of mpox among people with and without HIV. We identified 150 people with mpox (median age 36 years, 99.3% male, 92.7% reporting sex with other men). HIV status was available for 144 individuals, 58 (40.3%) of whom were HIV positive (only 3/58 had CD4 cell counts <200 cells/mm

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AIDS Research and Human Retroviruses

Volume

39

Issue

11

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