Role of Silodosin Pre-ureteroscopy: A Systematic Review and Meta-analysis of Randomised Controlled Trials
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Introduction: Ureteroscopy (URS) is a urologic procedure commonly performed for the management of upper urinary tract stones. However, URS can be challenging due to potential ureteral "tightness" and associated difficulty with instrument passage. Silodosin, an alpha-1 adrenergic receptor antagonist, may facilitate access by relaxing ureteral smooth muscle leading to an improvement in URS outcomes.
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European Urology Open Science