A retrospective observational study evaluating the safety and effectiveness of commercially available automated insulin delivery systems in people with type 1 diabetes and gastroparesis

Abstract

AIMS: A retrospective observational cohort study evaluating real-world outcomes in adults with type 1 diabetes and gastroparesis using automated hybrid closed loop insulin delivery systems (HCL). MATERIALS AND METHODS: All adults with type 1 diabetes and gastroparesis attending King's College Hospital diabetes service and using continuous glucose monitoring (CGM) from 5 October 2023 to 16 January 2025 were included. Glycaemic data (HbA RESULTS: From 1827 clinic attendees, 36 adults with gastroparesis were identified, with 17 initiating HCL. HCL and non-HCL groups had comparable baseline characteristics and metrics (HCL: Mean(SD) HbA CONCLUSIONS: Within a specialist multidisciplinary team setting, HCL systems significantly reduce HbA