Management of pregnancy and childbirth in Glanzmann thrombasthenia: A case series and review

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Rutten,Karlijn H. G.;Tsiamita,Olga;Van Thillo,Quentin;Raheja,Priyanka;Kaler,Mandeep;van Galen,Karin P. M.;Hogg,Matthew;Bowles,Louise;Schutgens,Roger E. G.;Sivapalaratnam,Suthesh

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2025

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To illustrate the challenges in the management of women with Glanzmann thrombasthenia (GT) planning a pregnancy, we conducted a literature review and present a case series of eight women giving detailed descriptions of reproductive health problems, platelet alloimmunisation, treatment to prevent post-partum haemorrhage and neonatal outcomes. ART, assisted reproductive therapy; PPH, post-partum haemorrhage; rFVIIa, recombinant activated factor VII.

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British journal of haematology

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