Randomized trial – PrEscription of intraDialytic exercise to improve quAlity of life in patients receiving hemodialysis
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Authors
Greenwood, Sharlene A.
Koufaki, Pelagia
Macdonald, Jamie H.
Bhandari, Sunil
Burton, James O.
Dasgupta, Indranil
Farrington, Kenneth
Ford, Ian
Kalra, Philip A.
Kean, Sharon
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Issue Date
2021
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Article
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Abstract
INTRODUCTION: Whether clinically implementable exercise interventions in people receiving hemodialysis (HD) therapy improve health-related quality of life (HRQoL) remains unknown. The PrEscription of intraDialytic exercise to improve quAlity of Life METHODS: In a multicenter, single-blinded, randomized, controlled trial, people receiving HD were randomly assigned to (i) intradialytic exercise training (exercise intervention group [EX]) and (ii) usual care (control group [CON]). Primary outcome was change in Kidney Disease Quality of Life Short-Form Physical Component Summary (KDQOL-SF 1.3 PCS) from baseline to 6 months. Cost-effectiveness was determined using health economic analysis; physiological impairment was evaluated by peak oxygen uptake; and harms were recorded. RESULTS: We randomized 379 participants; 335 and 243 patients (EX CONCLUSIONS: A 6-month intradialytic aerobic exercise program was not clinically beneficial in improving HRQoL as delivered to this cohort of deconditioned patients on HD.
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Kidney International Reports
Volume
6
Issue
8