Translating Ambulatory Cuffless Wrist Blood Pressure Estimates to Cuffed Blood Pressure Equivalents for Clinical Decision-Making: the Continuum Bp Study

Abstract

Objective: Current hypertension guidelines do not recommend cuffless wrist blood pressure (BP) devices for clinical use. Yet their prevalent use continues to rise. Clinicians are therefore confronted with cuffless BP data without a valid evidence-based framework for interpretation and decision making. In the Continuum BP study, we aimed to develop equations to translate BP estimates from two wrist BP devices employing distinct cuffless technologies-photoplethysmography (PPG; Aktiia/Hilo) and applanation tonometry (AT; Healthstats BPro Evo)-into corresponding 24-hour ambulatory BP monitoring (ABPM) values to support clinical use. Copyright © 2026 Lippincott Williams & Wilkins