Non-convulsive status epilepticus: COVID-19 or clozapine induced?
No Thumbnail Available
Authors
Sokolov, Elisaveta
Hadavi, Shahrzad
Mantoan Ritter, Laura
Brunnhuber, Franz
Check for full-text access
Issue Date
2020
Type
Article
Language
Keywords
Alternative Title
Abstract
We present a case of non-convulsive status epilepticus in a 57-year-old woman with a schizoaffective disorder, without an antecedent seizure history, with two possible aetiologies including SARS-CoV-2 infection and clozapine uptitration. We discuss the presentation, investigations, differential diagnosis and management. In particular, we focus on the electroencephalogram (EEG) findings seen in this case and the electroclinical response to antiepileptic medication. We review the literature and discuss the relevance of this case to the SARS-CoV-2 global pandemic. We emphasise the importance of considering possible neurological manifestations of SARS-CoV-2 infection and highlight seizure disorder as one of the possible presentations. In addition, we discuss the possible effects of clozapine on the electroclinical presentation by way of possible seizure induction as well as discuss the possible EEG changes and we highlight that this needs to be kept in mind especially during rapid titration.
Description
Citation
Publisher
License
Journal
BMJ Case Reports
Volume
13
Issue
10