TCT-782 Racial Disparities in the Outcomes of Spontaneous Coronary Artery Dissection: Real-World 5-Year Data
No Thumbnail Available
Authors
Abdulelah Z.
Alkhatib A.
Obeidat K.
Hassan M.
Abdulelah, A.
Check for full-text access
Issue Date
2025
Type
Article
Language
Keywords
Alternative Title
Abstract
Background: Spontaneous coronary artery dissection (SCAD) is known to be more common among females than males. However, limited data is available in regard to potential racial and ethnic differences. Therefore, it is of significance to evaluate for any ethnic and racial disparities in regard to SCAD outcomes. Method(s): Data was retrieved from the US Collaborative Network in TriNetX to evaluate for differences in SCAD outcomes between White and African American/Black race. Patients aged 18 years old and above who were diagnosed with SCAD and identified as White race or African American/Black were included. The investigated outcomes were major adverse cardiovascular events (MACE) at 30-days, 1-year and 5-year. Kaplan-Meier Survival analysis and Measure of Association Analysis were performed. Propensity score match analysis was performed to balance clinical characteristics. Result(s): Overall, a total of 1,977 patients were in each racial group following propensity score matching. Mortality due to combined MACE events was not significantly different between the white cohort and the African American/black cohort at 30-days, 6-months or 1-year interval. However, at 5-year interval, mortality due to combined MACE events was significantly lower in the white racial group (p=0.024), Hazard Ratio 0.918. Measure of association revealed a risk difference of -0.022 RR 0.968, OR 0.905. Stratification by each outcome revealed that mortality due to heart failure was statistically significantly less among the white racial cohort (p=0.007). Measure of association revealed a risk difference of -0.031, RR 0.836, OR 0.805. This statistically significant finding persisted at 6-months, 1-year and 5-year. In regard to mortality due to stroke, patients in the white racial group had a statistically significant lower risk at 5-year interval (p<0.001) and a risk difference of -0.031, RR 0.691, OR 0.668. Conclusion(s): African American/black race appears to be associated with higher risk of heart failure and death due to heart failure following a SCAD event even at 30-days interval. Additionally, African American/black patients are also at a higher risk of death due to stroke and combined MACE outcomes at 5-year interval. Categories: CORONARY: Acute Coronary Syndromes Copyright © 2025
Description
Citation
Publisher
License
Journal
Journal of the American College of Cardiology