Advanced epithelioid haemangioendothelioma in a child presenting as deep vein thrombosis
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Authors
Shields, Timothy
Pace, Erika
Height, Sue
Angelini, Paola
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Issue Date
2024
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Article
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Abstract
Venous thromboembolism (VTE) is a rare event in children and does not usually trigger investigation for malignancy. We report the case of a previously healthy female teenager presenting with unilateral leg swelling. Colour-Doppler ultrasound confirmed deep vein thrombosis (DVT), and the thrombophilia workup was negative. Cross-sectional imaging identified multiple liver and lung lesions, diagnosed as epithelioid haemangioendothelioma (EHE) at biopsy. Lifelong anticoagulation was commenced; the patient was initially observed and then started on sirolimus at disease progression. We describe the first published case of EHE presenting with DVT in a child. Clinicians need to be mindful of the association between cancer and thrombosis, even in paediatric patients.
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BMJ Case Reports
Volume
17
Issue
12