A pragmatic approach to the investigation of stable chest pain: A UK, multi-centre, randomised trial to improve patient outcomes, quality of life and cost effectiveness (CE-MARC 3)

Abstract

Background: There remains uncertainty and debate about the optimal non-invasive diagnostic imaging strategy for patients with suspected coronary artery disease (CAD). Computed Tomography Coronary Angiography (CTCA) and functional imaging are both guideline-recommended, although comparative evidence in patients with intermediate-high pre-test likelihood (PTL) of CAD is limited.