ardiotoxicity of chemotherapeutic drugs: an update and future perspectives
No Thumbnail Available
Authors
Bannister, Clare
Cannata, Antonio
Bromage, Daniel I.
McDonagh, Theresa
Check for full-text access
Issue Date
2022
Type
Article
Language
Keywords
Alternative Title
Abstract
Rapid advancements in oncological treatments over the past few decades have led to a significant improvement in cancer outcomes. Chemotherapeutic agents play a pivotal role in cancer treatment, with almost one-third of patients receiving them during their cancer treatment in the United Kingdom. The success of chemotherapeutic drugs has, however, resulted in an increasing incidence of cardiovascular side effects and complications. The most common cardiac manifestation is the development of cardiotoxicity, defined as the development of left ventricular systolic dysfunction, after treatment. This article provides an up-to-date review of the commonly used chemotherapeutic agents that cause cardiotoxicity and discusses current treatment options and evidence gaps.
Description
Citation
Publisher
License
Journal
Journal of Cardiovascular Pharmacology
Volume
80
Issue
4