A pragmatic randomized controlled trial of cognitive therapy for post-traumatic stress disorder in children and adolescents exposed to multiple traumatic stressors: the DECRYPT</scp> trial
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Authors
Meiser-Stedman, Richard
Allen, Leila
Ashford, Polly-Anna
Beeson, Ella
Byford, Sarah
Danese, Andrea
Farr, A.
Finn, Jack
Goodall, Ben
Grainger, Lauren
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Issue Date
15/09/2025
Type
Journal article
Language
Keywords
Mental Health
Alternative Title
Abstract
Trauma-focused cognitive-behavioral therapies (TF-CBTs) are efficacious in children and adolescents with post-traumatic stress disorder (PTSD). However, there is limited evidence in youth exposed to multiple traumas, especially in real-world settings. This paper reports on a pragmatic randomized controlled trial (RCT) evaluating whether one form of TF-CBT, cognitive therapy for PTSD (CT-PTSD), was effective for PTSD following multiple trauma exposure in 8-17 year-olds attending UK mental health services, relative to treatment-as-usual (TAU).
Description
Citation
World Psychiatry. 2025 Oct;24(3):422-434. doi: 10.1002/wps.21355. PMID: 40948050; PMCID: PMC12434375.
Publisher
License
Journal
World Psychiatry
Volume
24
Issue
3