Hyperspectral abdominal laparoscopy with real-time quantitative tissue oxygenation imaging: a live porcine study
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Authors
MacCormac, Oscar
Horgan, Conor C.
Waterhouse, Dale
Noonan, Philip
Janatka, Mirek
Miles, Richard
Jacobs, Jaco
Dockerill, Cameron
Trotouin, Théo
Schizas, Alexis
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2025
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Article
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BACKGROUND: Ischaemia is a critical complication, and can result in poor surgical outcomes. While intra-operative overt ischaemia can be perceived with the naked eye, timely recognition of borderline perfusion can prevent post-operative ischaemic complications, which is particularly relevant for colorectal anastomoses. Consequently, there is a clinical need for new technologies to intra-operatively assess tissue oxygenation (indicative of end organ perfusion), with minimal disruption to the surgical workflow. Here we present a hyperspectral imaging (HSI) system for laparoscopic surgery. This system provides live, easy to interpret, tissue oxygenation (StO METHODS: White light view and tissue oxygenation maps were reconstructed from a protoype laparoscopic Hyperspectral Surgical System (HSS). First, in a live porcine model (55 kg female), the mesentery of a small bowel loop was temporarily occluded with a laparoscopic grasper, then released whilst being imaged with HSI. The quantitative StO RESULTS: The HSS was used as the primary scope to complete a laparoscopic colorectal anastomosis, providing a simultaneous white light view and hyperspectral information. Quantitative results from small bowel imaging were shown to correlate with measurements from the superficial tissue oximetry probe. Real-time tissue oxygenation maps were shown to visually correlate with ICG-FA. CONCLUSION: The HSS can guide laparoscopic surgical procedures whilst providing visual and quantitative tissue oxygenation information in a live animal model. This paves the way for further studies to assess clinical applications.
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Frontiers in Medical Technology
Volume
7