The association between disordered eating and psychosis in clinical and non-clinical populations: a systematic review and meta-analysis
No Thumbnail Available
Authors
Drymonitou, Georgia
McCulloch, Amy
Parry, Sarah
Gough, Rhia
Cruz, Rodrigo Moreira
Mostoufi, Mia
Jawad, Mariam
Newman, Charlotte
Harding, Duncan
Pablo, Gonzalo Salazar de
Check for full-text access
Issue Date
28/05/2025
Type
Journal article
Language
Keywords
Mental Health
Alternative Title
Abstract
Background Eating disorders and psychotic disorders represent two of the most serious psychiatric conditions. Emerging lines of evidence from genetic and epidemiological studies suggest that these disorders may commonly co-occur. This systematic review investigated the association between these disorders across community and clinical populations. Method A systematic review was preregistered (CRD42021231771) and conducted according to PRISMA guidelines. Web of Science, PsycINFO and Medline were searched for articles on the association and comorbidity between psychosis and eating disorders up to the 26th February 2024. A random effects meta-analysis was conducted for studies reporting comorbidity of eating disorders and psychotic disorders based on clinical diagnosis or interview measures, to estimate prevalence of the comorbidity between these disorders. A narrative synthesis was conducted for all other studies and grouped by sample (general population, eating disorders or psychotic disorders). Results In total 43 studies met inclusion criteria for the systematic review and 16 were included in the meta-analysis. Findings suggest substantial comorbidity between eating disorders and psychotic disorders, with a pooled comorbidity prevalence of 8% (CI: 3, 14) based on clinical diagnosis or interview measures. Studies using self-report questionnaires also highlight the association between eating disorders and psychosis across clinical and community populations. Conclusions Eating disorders and psychotic disorders frequently co-occur. Further research should investigate the temporal order of symptom development and consider the need for novel interventions targeted at overlapping psychotic and eating disorder symptoms and associated phenomena.
Description
Citation
Psychological Medicine, 55, e160. doi:10.1017/S003329172500114X
Publisher
License
Journal
Psychological Medicine
Volume
55